polypharmacy

noun

poly·​phar·​ma·​cy ˌpä-li-ˈfär-mə-sē How to pronounce polypharmacy (audio)
: the practice of administering many different medicines especially concurrently for the treatment of a single disease
also : the concurrent use of multiple medications by a patient to treat usually coexisting conditions and which may result in adverse drug interactions

Examples of polypharmacy in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Another larger issue is polypharmacy, which is the regular use of 5 or more medications at the same time. Sophie Okolo, Forbes, 9 Oct. 2024 But taking many medicines simultaneously, known among medical experts as polypharmacy, increases people’s risk of experiencing severe side effects and drug interactions, said Dr. Nina Blachman, an associate professor of medicine and geriatrics at the New York University Grossman School of Medicine. Knvul Sheikh, San Diego Union-Tribune, 14 May 2024 That practice, called polypharmacy, can increase the likelihood of harmful side effects, the suit said. Darcy Costello, Baltimore Sun, 17 Jan. 2023 Instances of polypharmacy do not always begin with a diagnosis of A.D.H.D. Matt Richtel Annie Flanagan, New York Times, 27 Aug. 2022 Similarly, the use of dimensions as key secondary end points in many different diagnostic categories may lead to pseudospecific indications and polypharmacy. Neuroskeptic, Discover Magazine, 3 Aug. 2012

Word History

First Known Use

1762, in the meaning defined above

Time Traveler
The first known use of polypharmacy was in 1762

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Cite this Entry

“Polypharmacy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polypharmacy. Accessed 12 Sep. 2025.

Medical Definition

polypharmacy

noun
poly·​phar·​ma·​cy -ˈfär-mə-sē How to pronounce polypharmacy (audio)
plural polypharmacies
: the practice of administering many different medicines especially concurrently for the treatment of the same disease
also : the concurrent use of multiple medications by a patient to treat usually coexisting conditions and which may result in adverse drug interactions
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