polymerase chain reaction

noun

: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
abbreviation PCR

Examples of polymerase chain reaction in a Sentence

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These include sophisticated machine-learning methods applied to medical data, cost-effective microfluidic and other lab-on-a-chip systems, and faster and cheaper laboratory tests such as rapid polymerase chain reaction (PCR) for DNA analysis. Evan Ackerman, IEEE Spectrum, 29 May 2015 In an August 2023 letter published in Therapies, Bik and colleagues noted the cutoff for classifying a polymerase chain reaction test as positive was different in the treatment and control groups. Bycathleen O’Grady, science.org, 17 Dec. 2024 Your healthcare provider can test your blood for antibodies to the virus using a polymerase chain reaction (PCR) blood test.4 Treatments for Varicella-Zoster Virus The goal of varicella-zoster treatment is to improve the symptoms and shorten the time of illness. Carrie Madormo, Rn, Health, 3 Nov. 2024 But in 1984, the American biochemist Kary Mullis invented polymerase chain reaction (PCR), a method of amplifying very small amounts of DNA so it can be studied in detail. David Cox, WIRED, 2 Dec. 2020 See All Example Sentences for polymerase chain reaction

Word History

First Known Use

1985, in the meaning defined above

Time Traveler
The first known use of polymerase chain reaction was in 1985

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Cite this Entry

“Polymerase chain reaction.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polymerase%20chain%20reaction. Accessed 4 Mar. 2025.

Medical Definition

polymerase chain reaction

noun
: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, binding a primer to each single strand at the end of the given DNA segment where synthesis will start, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
abbreviation PCR

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