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Throughout life, our bone tissue is maintained by bone-building osteoblasts working in harmony with counterpart cells called osteoclasts, which break down old bone that needs replacing.—Jolene Edgar, Allure, 11 Feb. 2025 Manganese is also involved in skeletal health by regulating the activity of osteoblasts and osteoclasts, specialized cells that build up and break down bone tissue, respectively.6
Manganese is also required to produce collagen, a major component of bone tissue and your skin.—Jillian Kubala, Health, 5 Feb. 2025 When those cells outnumber the osteoblasts, though, there's an overall loss of bone tissue, resulting in weaker, more fragile bones.—Ben Coxworth, New Atlas, 2 Feb. 2025 In modern skeletons, tiny blood vessels that burrow into the bone’s hard matrix provide an inroad for cells called osteoclasts to eat away old bone and for cells called osteoblasts to begin making new bone.—Byelizabeth Pennisi, science.org, 10 Jan. 2025 Magnesium also helps the body make key enzymes that stimulate production of osteoblasts (new bone cells).—Bryant Stamford, The Courier-Journal, 5 Dec. 2024 Lab research shows that flavonoids may increase the activity of bone-forming cells (osteoblasts) and decrease the activity of bone-degrading cells (osteoclasts).12
7.—Brittany Lubeck, Ms, Rdn, Verywell Health, 28 Oct. 2024 In healthy patients with a bone fracture, after about two weeks, bodies begin to fill in the break with new bone cells—called osteoblasts.—IEEE Spectrum, 10 Dec. 2023 Bone metabolism is characterized by the reabsorption of bone by osteoclast cells and the laying down of new bone by osteoblast cells.—Dr. Keith Roach, oregonlive, 30 Aug. 2022
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