off-label

adjective

off-la·​bel ˈȯf-ˌlā-bəl How to pronounce off-label (audio)
: of, relating to, or being a drug used to treat a condition for which it has not been officially approved

Examples of off-label in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recently, these medications have become extremely popular, in part due to off-label use. Erica Sloan, SELF, 20 May 2025 That’s the environment that encouraged Republicans in the Missouri legislature to pass the bill that explicitly banned pharmacists from speaking to patients about the potential dangers of using the drugs off-label. Suzanne King, Kansas City Star, 13 May 2025 Why Experts Think Taking Methylene Blue Is Risky Methylene blue can be prescribed off-label for a variety of purposes, including vasoplegic syndrome (a type of shock that can happen during heart procedures), Lyme disease, and as an add-on to cancer therapy. Tom Gavin, EverydayHealth.com, 12 May 2025 Nonetheless, the significance of the results means that patients with psoriasis of the scalp and body might want to consult their treating medical practitioner to discuss an off-label prescription for roflumilast foam. Paul McClure 07, New Atlas, 7 May 2025 See All Example Sentences for off-label

Word History

First Known Use

1987, in the meaning defined above

Time Traveler
The first known use of off-label was in 1987

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Cite this Entry

“Off-label.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/off-label. Accessed 3 Jun. 2025.

Medical Definition

off-label

adjective
off-la·​bel ˌȯf-ˌlā-bəl How to pronounce off-label (audio)
: of, relating to, or being an approved drug legally prescribed or a medical device legally used by a physician for a purpose (as the treatment of children or of a certain disease or condition) for which it has not been specifically approved (as by the United States Food and Drug Administration)
the off-label use of oral contraceptives to treat dysmenorrhea
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