estradiol

noun

es·​tra·​di·​ol ˌe-strə-ˈdī-ˌȯl  -ˌōl 

: a natural estrogenic hormone that is a phenolic alcohol C₁₈H₂₄O₂ secreted chiefly by the ovaries, that is the most potent of the naturally occurring estrogens, and that is administered in its natural or semisynthetic esterified form especially to treat menopausal symptoms

Examples of estradiol in a Sentence

Recent Examples on the Web

Therefore, a decline in estradiol during menopause can contribute to hypertension (high blood pressure).8 Sodium significantly affects hypertension.14 People with ovaries can be more sensitive to sodium during the menopause transition, which can lead to edema (fluid retention) in the limbs. —Merve Ceylan, Health, 27 Dec. 2024

Women who are susceptible to migraines tend to experience a faster rate of estradiol decline around the time of their period compared to women who don’t. —Lori Youmshajekian, WIRED, 23 Sep. 2024

Within three months, most of the transgender men’s testosterone levels entered the typical range for cisgender men while their estradiol (the most potent form of estrogen that is made in the body) and progesterone levels decreased. —Tanya Lewis, Scientific American, 4 Sep. 2024

It is characterized by high follicle-stimulating hormone (FSH) levels, low estradiol (estrogen) levels, and vasomotor symptoms. —Joy Emeh, Health, 18 July 2024

Word History

Etymology

International Scientific Vocabulary estra- (from estrane parent compound of estradiol, from New Latin estrus + English -ane) + di- + -ol entry 1

First Known Use

1934, in the meaning defined above

Phrases Containing estradiol

• ethinyl estradiol

Medical Definition

estradiol

noun

es·​tra·​di·​ol ˌes-trə-ˈdī-ˌȯl  -ˌōl 

variants or chiefly British oestradiol

ˌē-strə-ˈdī-ˌȯl  ē-ˈstrad-ē-ˌȯl 

-ˌōl

: a natural estrogenic hormone that is a phenolic alcohol C₁₈H₂₄O₂ secreted chiefly by the ovaries, is the most potent of the naturally occurring estrogens, and is administered in its natural or semisynthetic esterified form especially to treat menopausal symptoms

called also dihydrotheelin

see estrace, estraderm, estring