multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor

Examples of multiple sclerosis in a Sentence

Recent Examples on the Web

Elsa Mendoza was diagnosed with multiple sclerosis, an autoimmune disease that attacks the central nervous system, 18 years ago. —Ralph D. Russo, New York Times, 14 Dec. 2025

The initial results were inconclusive, but further testing over the next week, to rule out the possibility of a brain or spinal tumor, ultimately led to a diagnosis of multiple sclerosis. —Andrew Abrahams, PEOPLE, 11 Dec. 2025

The scans are often used to check for aneurysms of cerebral vessels, conditions of the eye and inner ear, multiple sclerosis, spinal cord conditions, stroke, tumors and brain injury from trauma. —Robert Birsel, MSNBC Newsweek, 10 Dec. 2025

Pryor also had long struggles with multiple sclerosis and drug addiction. —Lorenzino Estrada, AZCentral.com, 10 Dec. 2025

Word History

First Known Use

1885, in the meaning defined above

Rhymes for multiple sclerosis

• actinomycosis
• atherosclerosis
• endometriosis
• erythematosus
• erythroblastosis
• granulomatosis
• hemochromatosis
• histiocytosis
• hyperkeratosis
• ketoacidosis
• mononucleosis
• osteonecrosis

Kids Definition

multiple sclerosis

noun

: a disease marked by patches of hardened tissue in the brain or spinal cord resulting in symptoms (as weakness or paralysis in the arms or legs or loss of balance and muscle coordination) that usually come and go

Medical Definition

multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor