1
: a chromosome lacking a synaptic mate
especially : an unpaired X chromosome
2
: a single ribosome

Word History

First Known Use

1906, in the meaning defined at sense 1

Time Traveler
The first known use of monosome was in 1906

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Cite this Entry

“Monosome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/monosome. Accessed 15 Apr. 2025.

Medical Definition

1
: a chromosome lacking a synaptic mate
especially : an unpaired X chromosome
2
: a single ribosome
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