Menkes' disease

noun

Men·​kes' disease ˈmeŋ-kəz-, -kə-səz- 

: a disorder of copper metabolism that is inherited as a recessive X-linked trait and is characterized by a deficiency of copper in the liver and of copper-containing proteins (as ceruloplasmin) which results in intellectual disability, brittle kinky hair, and typically a fatal outcome early in life

called also Menkes' syndrome