melanoma

noun

mel·​a·​no·​ma ˌme-lə-ˈnō-mə 

plural melanomas also melanomata ˌme-lə-ˈnō-mə-tə 

1

: a tumor containing dark pigment

2

: a highly malignant tumor that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

Examples of melanoma in a Sentence

Recent Examples on the Web

In 2022, Mellencamp was diagnosed with stage II melanoma, which was promptly removed. —Armando Tinoco, Deadline, 12 Feb. 2025

Additionally, 132,000 melanoma skin cancers occur globally each year, with Australia — where Chambers resides — having one of the highest incidence and mortality rates. —Vanessa Etienne, People.com, 3 Feb. 2025

Overall, the cancer mortality rate declined by 34% between 1991 and 2022 in the United States, but incidents rates continue to rise in common cancers like breast, pancreatic, uterine corpus, melanoma, liver and some oral cancers. —Mary Whitfill Roeloffs, Forbes, 16 Jan. 2025

At times Jimmy Carter could seem like a Superman, coming back in 2015 from melanoma that had spread to his brain and liver. —Rita Braver, CBS News, 5 Jan. 2025

Word History

Etymology

melan- (in melanosis, melanotic) + -oma

First Known Use

1838, in the meaning defined at sense 1

Phrases Containing melanoma

• malignant melanoma

Kids Definition

melanoma

noun

mel·​a·​no·​ma ˌmel-ə-ˈnō-mə 

plural melanomas also melanomata -mət-ə 

: a usually malignant tumor containing dark pigment

Medical Definition

melanoma

noun

mel·​a·​no·​ma ˌmel-ə-ˈnō-mə 

plural melanomas also melanomata -mət-ə 

1

: a benign or malignant skin tumor containing dark pigment

2

: a tumor of high malignancy that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

called also malignant melanoma, melanocarcinoma, melanoepithelioma, melanosarcoma