malignant

adjective

ma·​lig·​nant mə-ˈlig-nənt How to pronounce malignant (audio)
1
: tending to produce death or deterioration
malignant malaria
especially : tending to infiltrate, metastasize, and terminate fatally
a malignant tumor
2
a
: evil in nature, influence, or effect : injurious
a powerful and malignant influence
b
: passionately and relentlessly malevolent : aggressively malicious
the malignant tongues of gossipers
c
obsolete : malcontent, disaffected
malignantly adverb

Examples of malignant in a Sentence

a highly malignant form of cancer a powerful and malignant influence
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Further testing turned out that the tumor was malignant. Chris Hays, The Orlando Sentinel, 29 May 2025 Phelan graduated high school in May 2024, and days before starting her freshman year of college, was diagnosed with an inoperable stage 4 malignant brain tumor, a GoFundMe for her states. Viola Flowers, NBC news, 26 May 2025 My son Jack was diagnosed in 2022 with retinoblastoma, a malignant childhood cancer of the central nervous system that originates and grows in the eye. Dayna Copeland, The Mercury News, 15 Mar. 2025 According to a GoFundMe page set up in her name, Phelan was eventually diagnosed with a grade 4 malignant brain tumor that was categorized as a glioma, a growth of cells that starts in the brain or spinal cord, according to the Mayo Clinic. Skyler Caruso, People.com, 26 May 2025 See All Example Sentences for malignant

Word History

Etymology

Late Latin malignant-, malignans, present participle of malignari

First Known Use

1542, in the meaning defined at sense 2c

Time Traveler
The first known use of malignant was in 1542

Browse Nearby Words

Cite this Entry

“Malignant.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/malignant. Accessed 17 Jun. 2025.

Kids Definition

malignant

adjective
ma·​lig·​nant mə-ˈlig-nənt How to pronounce malignant (audio)
1
: evil in influence or effect : injurious
2
3
: tending to produce death
malignant tumors
malignantly adverb

Medical Definition

malignant

adjective
ma·​lig·​nant mə-ˈlig-nənt How to pronounce malignant (audio)
1
: tending to produce death or deterioration
malignant malaria
especially : tending to infiltrate, metastasize, and terminate fatally
malignant tumors
compare benign sense 1
2
: of unfavorable prognosis : not responding favorably to treatment
psychotic reactions with a malignant trend

More from Merriam-Webster on malignant

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