: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also lysergic acid diethylamide

Examples of LSD in a Sentence

Recent Examples on the Web
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Handler also addressed taking LSD during her recent 50th birthday celebrations in February. Becca Longmire, People.com, 28 Mar. 2025 It’s classified as a Schedule 1 drug like heroin and LSD, other drugs with high potential for abuse. Meena Duerson, CNN, 25 Mar. 2025 Simply turn in, hit the accelerator after the apex, and let that capable LSD pull you round. James Morris, Forbes, 22 Mar. 2025 Court records show James drank up to 24 beers at a party, downed some gin and also took LSD before returning to his room at Dick's house. arkansasonline.com, 21 Mar. 2025 See All Example Sentences for LSD

Word History

Etymology

borrowed from German, from Lysergsäure-Diäthylamid "lysergic acid diethylamide"

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of LSD was in 1950

Browse Nearby Words

Cite this Entry

“LSD.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/LSD. Accessed 15 Apr. 2025.

Kids Definition

: an illegal drug that causes abnormal sensations, extreme and changeable states of emotion, unnatural changes in the way time and space are experienced, and hallucinations and that may sometimes cause panic in response to the effects experienced

Medical Definition

: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also acid, lysergic acid diethylamide, lysergide

More from Merriam-Webster on LSD

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