lesion

noun

le·​sion ˈlē-zhən How to pronounce lesion (audio)
1
2
: an abnormal change in structure of an organ or part due to injury or disease
especially : one that is circumscribed (see circumscribe sense 1) and well defined
lesioned adjective

Examples of lesion in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Quantitative Insight: Software measures lesion size, growth rate and tissue composition with sub-millimeter precision, turning qualitative impressions into actionable numbers for personalized care. Yidi Xu, Forbes.com, 26 June 2025 Skin lesions, particularly gray patches, are becoming more prevalent in southern resident orcas, Weiss added, so allokelping might be a way to treat those lesions. Marlowe Starling, CNN Money, 23 June 2025 Nearly 500,000 people are diagnosed with Lyme disease each year in the U.S. For about 75% of them, the first sign will be a skin lesion that appears one to four weeks after being bitten by an infected deer tick. Angela Haupt, Time, 18 June 2025 Would that early liver tumor—or that pancreatic lesion—have proved fatal without intervention? Siddhartha Mukherjee, New Yorker, 16 June 2025 See All Example Sentences for lesion

Word History

Etymology

Middle English, from Anglo-French, from Latin laesion-, laesio, from laedere to injure

First Known Use

15th century, in the meaning defined at sense 1

Time Traveler
The first known use of lesion was in the 15th century

Browse Nearby Words

Cite this Entry

“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 4 Jul. 2025.

Kids Definition

lesion

noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
: a change in the structure of a bodily organ or part due to injury or disease
especially : an injured or diseased spot or area clearly marked off from healthy tissue around it

Medical Definition

lesion

1 of 2 noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
: an abnormal change in structure of an organ or part due to injury or disease
especially : one that is circumscribed and well defined
lesioned adjective

lesion

2 of 2 transitive verb
: to produce lesions in (as an animal's brain)

Legal Definition

lesion

noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
in the civil law of Louisiana : loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)

called also lesion beyond moiety

compare unjust enrichment
Etymology

Anglo-French, damage, injury, from Latin laesio, from laedere to injure

More from Merriam-Webster on lesion

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!