irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ə-tə-ˈbi-lə-tē 

plural irritabilities

1

: the quality or state of being irritable: such as

a

: quick excitability to annoyance, impatience, or anger : petulance

b

: abnormal or excessive excitability of an organ or part of the body

2

: the property of protoplasm and of living organisms that permits them to react to stimuli

Synonyms

• biliousness
• choler
• crankiness
• crossness
• crotchetiness
• grouchiness
• grumpiness
• huffiness
• irascibility
• irascibleness
• irritableness
• peevishness
• perverseness
• perversity
• pettishness
• petulance
• testiness
• waspishness

Examples of irritability in a Sentence

the librarian's well-known irritability makes students hesitant to ask questions

Recent Examples on the Web

Your personality or mood changes Several symptoms that aren’t memory-related are associated with early Alzheimer's and dementia, including irritability, depression, anxiety, and apathy. —Angela Haupt, Time, 25 Apr. 2025

Mood swings, irritability, headaches, acne, and cramps are some of the most common symptoms suffered by women during the week leading up to menstruation. —María Quiles, Vogue, 20 Mar. 2025

Sleeplessness: Lack of sleep can increase irritability. —Christopher Bergland, Verywell Health, 24 Apr. 2025

The result is that even a single night of drinking can lead to daytime fatigue, poor concentration and irritability. —Jesse Pines, Forbes.com, 21 Apr. 2025

Word History

First Known Use

1755, in the meaning defined at sense 2

Rhymes for irritability

• acceptability
• accessibility
• adaptability
• admissibility
• advisability
• affordability
• allowability
• amenability
• amiability
• appealability
• applicability
• availability

Kids Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the quality or state of being irritable

especially : readiness to become annoyed or angry

2

: the property of living tissue and living things that permits them to react to stimuli

Medical Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the property of protoplasm and of living organisms that permits them to react to stimuli

2

a

: quick excitability to annoyance, impatience, or anger

b

: abnormal or excessive excitability of an organ or part of the body (as the stomach or bladder)