irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ə-tə-ˈbi-lə-tē 

plural irritabilities

1

: the quality or state of being irritable: such as

a

: quick excitability to annoyance, impatience, or anger : petulance

b

: abnormal or excessive excitability of an organ or part of the body

2

: the property of protoplasm and of living organisms that permits them to react to stimuli

Synonyms

• biliousness
• choler
• crankiness
• crossness
• crotchetiness
• grouchiness
• grumpiness
• huffiness
• irascibility
• irascibleness
• irritableness
• peevishness
• perverseness
• perversity
• pettishness
• petulance
• testiness
• waspishness

Examples of irritability in a Sentence

the librarian's well-known irritability makes students hesitant to ask questions

Recent Examples on the Web

When their spouses don’t contribute, women can experience burnout, irritability and a deep, quiet resentment — not just toward the demands of work and family, but toward the relationship itself. —Mark Travers, Forbes.com, 21 Apr. 2025

Acute toxicity can also include nausea, vomiting, drowsiness, irritability and abdominal pain. —April Rubin, Axios, 31 Mar. 2025

For those who consume caffeine or energy drinks on a regular basis, this is the time frame at which the individual can experience withdrawal symptoms, which include headaches, irritability and constipation. —Jeff Goertzen, Orange County Register, 22 Mar. 2025

These can range from headaches to irritability and a general sense of malaise. —Matthew Adams, Fort Worth Star-Telegram, 19 Mar. 2025

Word History

First Known Use

1755, in the meaning defined at sense 2

Rhymes for irritability

• acceptability
• accessibility
• adaptability
• admissibility
• advisability
• affordability
• allowability
• amenability
• amiability
• appealability
• applicability
• availability

Kids Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the quality or state of being irritable

especially : readiness to become annoyed or angry

2

: the property of living tissue and living things that permits them to react to stimuli

Medical Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the property of protoplasm and of living organisms that permits them to react to stimuli

2

a

: quick excitability to annoyance, impatience, or anger

b

: abnormal or excessive excitability of an organ or part of the body (as the stomach or bladder)