irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ə-tə-ˈbi-lə-tē 

plural irritabilities

1

: the quality or state of being irritable: such as

a

: quick excitability to annoyance, impatience, or anger : petulance

b

: abnormal or excessive excitability of an organ or part of the body

2

: the property of protoplasm and of living organisms that permits them to react to stimuli

Synonyms

• biliousness
• choler
• crankiness
• crossness
• crotchetiness
• grouchiness
• grumpiness
• huffiness
• irascibility
• irascibleness
• irritableness
• peevishness
• perverseness
• perversity
• pettishness
• petulance
• testiness
• waspishness

Examples of irritability in a Sentence

the librarian's well-known irritability makes students hesitant to ask questions

Recent Examples on the Web

Symptoms include unexplained withdrawal, fear, sadness or irritability and not responding when comfort is given. —Josh Hammer, Newsweek, 20 Mar. 2025

Common symptoms include loud snoring, gasping for air, daytime fatigue, morning headaches, dry mouth, difficulty concentrating and irritability. —Maria Sokolina, Forbes, 25 Feb. 2025

Limiting Exposure to Lead Long-term exposure to lead and other heavy metals is tied to a variety of symptoms, including headaches, insomnia, and irritability, as well as to issues like heart disease and stroke. —Sam Walters, Discover Magazine, 25 Feb. 2025

Due to cognitive difficulties, this is especially disorienting for those with dementia and can escalate to feelings of confusion, anxiety, and irritability, says Meredith Bock, MD, a neurologist and Chief Medical Officer at Remo Health. —Cathy Habas, SELF, 17 Jan. 2025

Word History

First Known Use

1755, in the meaning defined at sense 2

Rhymes for irritability

• acceptability
• accessibility
• adaptability
• admissibility
• advisability
• affordability
• allowability
• amenability
• amiability
• appealability
• applicability
• availability

Kids Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the quality or state of being irritable

especially : readiness to become annoyed or angry

2

: the property of living tissue and living things that permits them to react to stimuli

Medical Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the property of protoplasm and of living organisms that permits them to react to stimuli

2

a

: quick excitability to annoyance, impatience, or anger

b

: abnormal or excessive excitability of an organ or part of the body (as the stomach or bladder)