inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue

2

: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation.

inflammations of the throat and ears

Recent Examples on the Web

If not treated early, the infection can progress to more serious symptoms, such as joint swelling and arthritis, nerve pain, tingling or numbness, facial muscle weakness, heart inflammation and difficulties with memory or concentration. —Emily Bache, The Conversation, 31 Mar. 2026

Unsaturated fat can improve cholesterol levels and reduce inflammation. —Emily Kay Votruba, EverydayHealth.com, 31 Mar. 2026

These medications tamp down inflammation in the body to help manage symptoms. —Korin Miller, SELF, 31 Mar. 2026

More uncommon but serious side effects, like acute pancreatitis (inflammation of the pancreas) and gallbladder issues, need immediate medical attention. —Nicole Hernandez, USA Today, 30 Mar. 2026

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing inflammation

• anti-inflammation

Rhymes for inflammation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: the act of inflaming : the state of being inflamed

2

: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue