inactivate

verb

in·​ac·​ti·​vate (ˌ)i-ˈnak-tə-ˌvāt How to pronounce inactivate (audio)
inactivated; inactivating; inactivates

transitive verb

: to make inactive
chemicals to inactivate viruses
inactivation noun

Examples of inactivate in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Cooking helps inactivate these compounds, Messer explains, but those with thyroid concerns may want to moderate their intake or consult a healthcare professional. Daryl Austin, USA Today, 7 Sep. 2025 And treating infectious milk before it’s dumped—perhaps with a weak acid such as vinegar or lemon juice to inactivate the virus, Lakdawala says—could keep H5N1 out of wastewater. Stephanie Pappas, Scientific American, 5 Aug. 2025 Female cats have two X-chromosomes, one of which is randomly inactivated early in embryonic development on a cell-by-cell basis (figures 1 & 2), giving rise to tortoiseshell or calico fur color patterns. Grrlscientist, Forbes.com, 2 June 2025 The activity of p53 in a cell is regulated by another gene known as MDM2 that encodes a protein that essentially inactivates the p53 protein. New Atlas, 20 May 2025 See All Example Sentences for inactivate

Word History

First Known Use

1906, in the meaning defined above

Time Traveler
The first known use of inactivate was in 1906

Browse Nearby Words

Cite this Entry

“Inactivate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/inactivate. Accessed 12 Sep. 2025.

Kids Definition

inactivate

verb
in·​ac·​ti·​vate (ˈ)in-ˈak-tə-ˌvāt How to pronounce inactivate (audio)
: to make inactive
inactivation noun

Medical Definition

inactivate

transitive verb
in·​ac·​ti·​vate (ˈ)in-ˈak-tə-ˌvāt How to pronounce inactivate (audio)
inactivated; inactivating
: to make inactive: as
a
: to destroy certain biological activities of
inactivate the complement of normal serum by heat
b
: to cause (as an infectious agent) to lose disease-producing capacity
inactivate bacteria
inactivation noun
inactivator noun
Last Updated: - Updated example sentences
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