idiopathic

adjective

id·​i·​o·​path·​ic ˌi-dē-ə-ˈpa-thik How to pronounce idiopathic (audio)
1
: arising spontaneously or from an obscure or unknown cause : primary
idiopathic epilepsy
2
: peculiar to the individual
idiopathically adverb

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Idiopathic joins the combining form idio- (from Greek idios, meaning "one's own" or "private") with -pathic, a form that suggests the effects of disease. The combining form idio- is typically found in technical terms. Examples include idiographic, meaning "relating to or dealing with something concrete, individual, or unique"; idiolect, meaning "the language or speech pattern of one individual at a particular period of life"; and idiotype, meaning "the molecular structure and conformation of an antibody that confers its antigenic specificity." A more common idio- word is idiosyncrasy, which most commonly refers to an unusual way in which a person behaves or thinks, or to an unusual part or feature of something.

Examples of idiopathic in a Sentence

Recent Examples on the Web
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It’s shown promising results in Phase 2a clinical studies across type 1 and type 2 narcolepsy and idiopathic hypersomnia, which is another form of excessive daytime sleepiness. Jeff Marks, CNBC, 31 Mar. 2026 Its lead drug has been tested in Phase 2 studies in different types of narcolepsy and idiopathic hypersomnia. Ed Silverman, STAT, 31 Mar. 2026 Since Simon has idiopathic epilepsy, Klee specializes in taking in medical foster dogs, as well as dogs who otherwise would be hard to adopt. Kate Aurthur, Variety, 8 Feb. 2026 One of the startup’s main efforts is a drug to tackle idiopathic pulmonary fibrosis, a condition where scar tissue forms in the lungs, making breathing difficult. Nicholas Gordon, Fortune, 22 Jan. 2026 See All Example Sentences for idiopathic

Word History

First Known Use

1669, in the meaning defined at sense 1

Time Traveler
The first known use of idiopathic was in 1669

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Cite this Entry

“Idiopathic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/idiopathic. Accessed 5 Apr. 2026.

Medical Definition

idiopathic

adjective
id·​io·​path·​ic ˌid-ē-ə-ˈpath-ik How to pronounce idiopathic (audio)
: arising spontaneously or from an obscure or unknown cause : primary
idiopathic epilepsy
idiopathic thrombocytopenic purpura
idiopathically adverb
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