hypothyroidism

noun

hy·​po·​thy·​roid·​ism ˌhī-pō-ˈthī-ˌrȯi-ˌdi-zəm 

: deficient activity of the thyroid gland

also : a resultant bodily condition characterized by lowered metabolic rate and general loss of vigor

Examples of hypothyroidism in a Sentence

Recent Examples on the Web

According to the National Institute of Diabetes and Digestive and Kidney Diseases, Hashimoto's disease is an autoimmune disorder that can cause hypothyroidism, or an underactive thyroid. —EW.com, 9 May 2025

While immunotherapies also come with side effects—including fatigue, skin rashes, and, in a few patients, hypothyroidism—these are often manageable. —Alice Park, Time, 28 Apr. 2025

Ignoring them puts you at risk of the imbalance manifesting into a more serious condition, like PCOS, hypothyroidism, and endometriosis. —Eman Bare, Essence, 21 Apr. 2025

Other reasons include nutritional deficiencies, hypothyroidism, parasites, exposure to sunlight, post-trauma healing or cancer. —Liz O'Connell, MSNBC Newsweek, 30 Apr. 2025

Word History

Etymology

International Scientific Vocabulary

First Known Use

1905, in the meaning defined above

Rhymes for hypothyroidism

• absolutism
• adventurism
• aestheticism
• africanism
• agnosticism
• alcoholism
• anabolism
• anachronism
• anglicanism
• antagonism
• arianism
• asceticism

Kids Definition

hypothyroidism

noun

hy·​po·​thy·​roid·​ism ˌhī-pō-ˈthī-ˌrȯid-ˌiz-əm 

: too little activity of the thyroid gland

also : the abnormal bodily condition that results from this

hypothyroid

-ˌrȯid

adjective

Medical Definition

hypothyroidism

noun

hy·​po·​thy·​roid·​ism -ˌiz-əm 

: deficient activity of the thyroid gland

also : a resultant bodily condition characterized by lowered metabolic rate and general loss of vigor