hyaluronidase

noun

hy·​al·​uron·​i·​dase ˌhī(-ə)l-yu̇-ˈrä-nə-ˌdās 

-ˌdāz

: a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid

Examples of hyaluronidase in a Sentence

Recent Examples on the Web

Before injection, often a test spot is performed on the skin to ensure that there is no sign of any immediate allergy to the hyaluronidase. —Jackie Fields, People.com, 15 Jan. 2025

The hyaluronidase is then directly injected into the site of the hyaluronic acid dermal filler, and then the area is massaged. —Jackie Fields, People.com, 15 Jan. 2025

Giving them a better idea of where to insert the hyaluronidase. —Celeste Polanco, Essence, 13 Sep. 2024

Anything that lasts beyond a week merits another visit to your practitioner for an assessment and possibly dissolving the product with hyaluronidase. —Loren Savini, Allure, 23 July 2024

Our doctors are quick to note that Topilase is absolutely not a dupe for conventional hyaluronidase. —Jolene Edgar, Harper's BAZAAR, 23 Dec. 2022

How does Topilase compare to injectable hyaluronidase? —Jolene Edgar, Harper's BAZAAR, 23 Dec. 2022

Contrary to popular belief, filler doesn’t dissolve very well, even with the help of hyaluronidase, the injectable enzyme meant to reverse hyaluronic acid filler almost immediately. —Hanna Lustig, Glamour, 14 Sep. 2022

That might mean adding a few more drops of filler or using a pinch of hyaluronidase to flatten out any minor puffiness. —Danielle Sinay, Glamour, 7 Sep. 2022

Word History

Etymology

International Scientific Vocabulary, from hyaluronic (acid) + -idase (as in glucosidase)

First Known Use

1940, in the meaning defined above

Rhymes for hyaluronidase

• aminopeptidase
• anticholinesterase
• carboxypeptidase
• ablaze
• airways
• allays
• always
• amaze
• anglaise
• appraise
• archways
• arrays

Medical Definition

hyaluronidase

noun

hy·​al·​uron·​i·​dase -ˈrän-ə-ˌdās, -ˌdāz 

: a mucolytic enzyme that splits and lowers the viscosity of hyaluronic acid facilitating the spreading of fluid through tissues either advantageously (as in the absorption of drugs) or disadvantageously (as in the dissemination of infection), that occurs in many normal tissues, in malignant growths, in invasive bacteria, and in certain venoms, and that is used especially to aid in the dispersion of fluids (as local anesthetics) injected subcutaneously for therapeutic purposes

called also spreading factor