1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This fits, as most of the study participants were diagnosed with high-grade tumors and most received treatment by way of chemo- and radiation therapy. New Atlas, 11 Mar. 2025 The Yankees, meanwhile, are down two starters, as Luis Gil is out with a high-grade lat strain and isn’t expected back until the summer. Gary Phillips, Chicago Tribune, 11 Mar. 2025 Gil recently suffered a high-grade lat strain, which a second MRI confirmed back in New York. Gary Phillips, New York Daily News, 6 Mar. 2025 The American League’s reigning Rookie of the Year has been shut down with a high-grade lat strain following an MRI, Aaron Boone told reporters on Monday. Gary Phillips, New York Daily News, 3 Mar. 2025 See All Example Sentences for high-grade

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 18 Apr. 2025.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Last Updated: - Updated example sentences
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