high-grade

adjective

ˈhī-ˈgrād 

1

: of superior grade or quality

high-grade bonds

2

a

: being near the upper or most favorable extreme of a specified range

b

: medically serious or life-threatening

a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web

Jack Hoffman, a beloved Nebraska Cornhuskers superfan, has tragically passed away at 19 years of a diffuse high-grade neuroepithelial tumor. —Michael Gfoeller and David H. Rundell, Newsweek, 16 Jan. 2025

Credit markets have remained firm, sending a reassuring macro message, yet the upward march in Treasury rates has meant high-grade corporate debt offers a pretty safe yield approaching 6%. —Michael Santoli, CNBC, 11 Jan. 2025

Ukraine gets a free army of (presumably) high-grade attack drones, and the Coalition members get useful experience and build their capacity to make more and better drones in future. —David Hambling, Forbes, 10 Jan. 2025

By 1953, this enabled the U.S. to import high-grade tungsten from the mine. —Duncan Money / Made By History, TIME, 8 Jan. 2025

Word History

First Known Use

1826, in the meaning defined at sense 1

Kids Definition

high-grade

adjective

ˈhī-ˈgrād

: of a better grade or quality

Medical Definition

high-grade

adjective

ˈhī-ˈgrād 

: being near the upper, most serious, or most life-threatening extreme of a specified range

high-grade gliomas

high-grade cervical dysplasia

compare low-grade