: a lipoprotein of blood plasma that is composed of a high proportion of protein with little triglyceride and cholesterol and that is correlated with reduced risk of atherosclerosis : good cholesterol compare ldl

Examples of HDL in a Sentence

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That’s because a lower body mass index, higher levels of HDL cholesterol, and lower blood pressure can all reduce dementia risk, says Dr. Budson, who wasn’t involved in the new study. Tom Gavin, EverydayHealth.com, 12 Feb. 2025 These include visceral fat, insulin resistance, inflammation triglycerides and HDL, all of which could actually be improved on very low-carbohydrate diets. Melissa Rudy, Fox News, 10 Feb. 2025 Research suggests that berry-rich diets can help reduce total cholesterol, LDL cholesterol, triglycerides, and blood pressure while increasing heart-protective high-density lipoprotein (HDL) cholesterol. Jillian Kubala, Rd, Health, 27 Jan. 2025 Metrics like blood pressure, HDL cholesterol, and A1C (which tracks blood glucose fluctuations over time) are all related, in part to exercise and aerobic fitness. Lauren Leffer, Popular Science, 16 Jan. 2025 See All Example Sentences for HDL

Word History

Etymology

high-density lipoprotein

First Known Use

1954, in the meaning defined above

Time Traveler
The first known use of HDL was in 1954

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Cite this Entry

“HDL.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HDL. Accessed 3 Mar. 2025.

Medical Definition

: a lipoprotein of blood plasma that is composed of a high proportion of protein with little triglyceride and cholesterol and that is associated with decreased probability of developing atherosclerosis

called also alpha-lipoprotein, good cholesterol, high-density lipoprotein

compare ldl, vldl
Last Updated: - Updated example sentences
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