gray matter

noun

1

: neural tissue especially of the brain and spinal cord that contains nerve-cell bodies as well as nerve fibers and has a brownish-gray color

2

: brains, intellect

Synonyms

• brain(s)
• brainpower
• headpiece
• intellect
• intellectuality
• intelligence
• mentality
• reason
• sense
• smarts

Examples of gray matter in a Sentence

she's got the gray matter to figure that equation out

Recent Examples on the Web

Social engagement mitigates cognitive decline and enhances gray matter in the brain. —Bryan Robinson, Forbes.com, 6 Apr. 2025

The team found that just one to two units of alcohol a day reduced overall brain volume and gray matter volumes across a number of areas, and microstructures in the white matter. —New Atlas, 28 Feb. 2025

The results revealed significant reductions in gray matter after 10 days of caffeine. —New Atlas, 11 Feb. 2025

Prior research has indicated caffeine consumption may be associated with acute reductions in gray matter volume. —New Atlas, 11 Feb. 2025

Word History

First Known Use

1809, in the meaning defined at sense 1

Rhymes for gray matter

• backscatter
• antimatter
• atter
• batter
• blatter
• catarrh
• chatter
• clatter
• fatter
• flatter
• hatter
• latter

Kids Definition

gray matter

noun

1

: nerve tissue especially of the brain and spinal cord that has a brownish gray color

2

: intelligence sense 1

Medical Definition

gray matter

noun

: neural tissue especially of the brain and spinal cord that contains cell bodies as well as nerve fibers, has a brownish gray color, and forms most of the cortex and nuclei of the brain, the columns of the spinal cord, and the bodies of ganglia

called also gray substance