glutamate

noun

glu·​ta·​mate ˈglü-tə-ˌmāt How to pronounce glutamate (audio)
: a salt or ester of glutamic acid
specifically : a salt or ester of levorotatory glutamic acid that functions as an excitatory neurotransmitter compare monosodium glutamate

Examples of glutamate in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
With astrocytes out of the picture, glutamate, a key neurotransmitter, spilled into extrasynaptic zones, flipping on NMDA receptors and revving up vasopressin neuron activity. Pranjal Malewar, New Atlas, 3 Sep. 2025 In summary, a target neurotransmitter is affected, such as glutamate, serotonin, dopamine and/or norepinephrine. Andre Mouchard, Oc Register, 18 Aug. 2025 Memantine Memantine works by preventing glutamate from attaching to the N-methyl-D-aspartate (NMDA) receptor (binding site). Ross Phan, Verywell Health, 12 Aug. 2025 Protein-rich seaweed is already naturally imbued with glutamates and needs no further processing, although drying increases the shelf life. Jeff Burkhart, Mercury News, 23 July 2025 See All Example Sentences for glutamate

Word History

First Known Use

1876, in the meaning defined above

Time Traveler
The first known use of glutamate was in 1876

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Cite this Entry

“Glutamate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/glutamate. Accessed 9 Sep. 2025.

Medical Definition

glutamate

noun
glu·​ta·​mate ˈglüt-ə-ˌmāt How to pronounce glutamate (audio)
: a salt or ester of glutamic acid
specifically : a salt or ester of levorotatory glutamic acid that functions as an excitatory neurotransmitter see monosodium glutamate

More from Merriam-Webster on glutamate

Last Updated: - Updated example sentences
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