genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Once that was done, the researchers started looking through the genomes of species that have been identified as breaking down industrial contaminants. ArsTechnica, 7 May 2025 The company’s project involved recovering DNA of the extinct dire wolf from a fossil tooth found in Idaho and an ear bone in Ohio, parts of the animal’s primordial habitat, but the key was its editing of a donor genome of the gray wolf to alter 14 of its genes. Michael Hiltzik, Los Angeles Times, 24 Apr. 2025 These approaches are higher up on the drug development tree; scientists have been discussing the promises of personalized medicine since a draft of the human genome sequence was completed in 2000. Paul Smaglik, Discover Magazine, 16 Apr. 2025 Fifteen edits were derived from Colossal’s study of the dire-wolf genome and five tweaks were derived from scrutiny of the gray-wolf genome. D. T. Max, New Yorker, 7 Apr. 2025 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 21 May. 2025.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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