follicle

noun

fol·​li·​cle ˈfä-li-kəl 

1

a

: a small anatomical cavity or deep narrow-mouthed depression

b

: a small lymph node

c

: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells

especially : graafian follicle

2

: a dry dehiscent one-celled many-seeded fruit (as of the milkweed) that has a single carpel and opens along one suture

follicular

fə-ˈli-kyə-lər 

fä-

adjective

Examples of follicle in a Sentence

Recent Examples on the Web

Laser hair removal relies on pigment in the hair root to absorb light energy and disable the follicle. —Leslie Baumann, Miami Herald, 1 Apr. 2026

Technically, the ovaries don’t show cysts, but arrested follicles. —Theresa Gaffney, STAT, 1 Apr. 2026

Other types of hair loss include alopecia areata, an autoimmune disease in which hair can often regrow because the follicles are not destroyed, and scarring alopecia, where the follicle’s root is permanently damaged. —Lily Hautau, CNN Money, 30 Mar. 2026

By revitalizing dormant follicles and promoting the transition from the telogen phase back to anagen, the Minoxidil hair regrowth treatment reduces the overall quantity of hair lost. —Kansas City Star, 27 Mar. 2026

Word History

Etymology

New Latin folliculus, from Latin, diminutive of follis bag — more at fool

First Known Use

1715, in the meaning defined at sense 1a

Phrases Containing follicle

• follicle mite
• follicle-stimulating hormone
• Graafian follicle
• hair follicle

Rhymes for follicle

• diabolical
• symbolical

Kids Definition

follicle

noun

fol·​li·​cle ˈfäl-i-kəl 

1

a

: a small cavity or a deep bodily depression with a narrow mouth (as one from which a hair grows)

b

: graafian follicle

2

: a dry one-celled fruit (as in the milkweed) that splits open by one seam when ripe

follicular

fə-ˈlik-yə-lər 

fä-

adjective

Medical Definition

follicle

noun

fol·​li·​cle ˈfäl-i-kəl 

1

: a small anatomical cavity or deep narrow-mouthed depression

especially : a small simple or slightly branched gland : crypt

2

: a small lymph node

3

: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells : ovarian follicle

especially : graafian follicle

follicular

fə-ˈlik-yə-lər, fä- 

adjective