: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
epinephrine is a fight-or-flight hormone
a fight-or-flight reaction

Examples of fight-or-flight in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Stimulating it, even briefly, can shift your body out of fight-or-flight and into calm. Allison Palmer, Fort Worth Star-Telegram, 6 May 2026 Mayo Clinic Press notes that anxiety triggers labored breathing, muscle tightening and activation of the sympathetic nervous system, the body’s fight-or-flight wiring. Allison Palmer, Miami Herald, 6 May 2026 Calms the Nervous System Response When anxiety spikes, the body shifts into fight-or-flight mode — and the breathing rate can amplify quickly, among other physical signs. Tom Gavin, EverydayHealth.com, 30 Apr. 2026 Chronic stress triggers the body's fight-or-flight response, leading to a steady release of stress hormones like cortisol. Lindsay Curtis, Verywell Health, 17 Apr. 2026 See All Example Sentences for fight-or-flight

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of fight-or-flight was in 1973

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Cite this Entry

“Fight-or-flight.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fight-or-flight. Accessed 16 May. 2026.

Medical Definition

fight-or-flight

adjective
ˌfī-tər-ˈflīt
: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
the fight-or-flight response
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