estrogen

noun

es·​tro·​gen ˈe-strə-jən 

: any of various natural steroids (such as estradiol) that are formed from androgen precursors, that are secreted chiefly by the ovaries, placenta, adipose tissue, and testes, and that stimulate the development of female secondary sex characteristics and promote the growth and maintenance of the female reproductive system

also : any of various synthetic or semisynthetic steroids (such as ethinyl estradiol) that mimic the physiological effect of natural estrogens

Examples of estrogen in a Sentence

Recent Examples on the Web

The recommendations, which were published in the medical journal Stroke, also warn that trans women who take the hormone estrogen for gender affirmation care may face a higher stroke risk. —Lauryn Higgins, Flow Space, 29 Oct. 2024

Oral Contraceptives People who have used oral contraceptives with higher estrogen content are twice as likely to experience a stroke later in life as people who use birth control pills with little or no estrogen, according to the guidelines. —Lisa Rapaport, EverydayHealth.com, 23 Oct. 2024

Rates of breast cancer in women under 50 have increased more than 15% in the last two decades, a rise that is almost entirely driven by an increase in estrogen receptor-positive breast cancer (ER+), a tumor subtype that needs the hormone estrogen to grow and spread. —Kaitlin Sullivan, NBC News, 19 Oct. 2024

During menopause, the reproductive hormones estrogen and progesterone decrease, and menstruation stops. —Carley Millhone, Health, 10 Oct. 2024

Word History

Etymology

estrus + -o- + -gen

Note: The word estrogen was originally a U.S. brand name for an extract of glandular tissue used in the treatment of ovarian dysfunction. Its producer, Parke, Davis and Company, relinquished rights to the name in 1936.

First Known Use

1927, in the meaning defined above

Phrases Containing estrogen

• estrogen replacement therapy
• selective estrogen receptor modulator

Kids Definition

estrogen

noun

es·​tro·​gen ˈes-trə-jən 

: a substance that tends to cause the development of secondary sex characteristics in the female and promote the growth and normal functioning of the female reproductive system

estrogenic

ˌes-trə-ˈjen-ik

adjective

Medical Definition

estrogen

noun

es·​tro·​gen ˈes-trə-jən 

variants or chiefly British oestrogen

ˈē-strə-jən 

: any of various natural steroids (as estradiol) that are formed from androgen precursors, that are secreted chiefly by the ovaries, placenta, adipose tissue, and testes, and that stimulate the development of female secondary sex characteristics and promote the growth and maintenance of the female reproductive system

also : any of various synthetic or semisynthetic steroids (as ethinyl estradiol) that mimic the physiological effect of natural estrogens

estrogen-like adjective

or estrogenlike

-ˌlīk 

an estrogen-like compound

estrogen-like effects