plural downers
1
: a depressant drug
especially
: barbiturate
… would often take the stage stoned on downers or high on acid … —Peter Keough
Suppressant drugs, referred to as "downers", help create feelings of relaxation and tiredness rather than the high that people get from taking "uppers" … —Izzy Lyons
2
: someone or something depressing, disagreeable, or unsatisfactory
Rain, biting insects, and soggy ground are other downers that keep me under cover.—Norman Strung
Losing in their conference tournaments was a major downer for the NC State and East Carolina baseball teams.—Brett Friedlander
3
: a weak, sick, or lame domesticated animal (such as a cow or pig) that is down and cannot get up
… the USDA last week instituted a series of measures to reassure consumers that American beef is safe, including a ban on the slaughter of cattle too sick or injured to walk, called downers, for human food.—Cathy Booth Thomas
—often used before another nouna downer cow
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Merriam-Webster unabridged
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