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Down syndrome
noun
variants
or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21
called also trisomy 21
Examples of Down syndrome in a Sentence
Recent Examples on the Web
For instance, a requirement that children must be potty trained by age three can be unattainable for some children with Down syndrome or autism.
—Rachelle Rutherford, Forbes, 29 Oct. 2024
This year's photo series features 62 individuals with Down syndrome ages 1 to 36.
—Anna Lazarus Caplan, People.com, 22 Oct. 2024
As a guest on the Wednesday, Oct. 16 episode of the Club Shay Shay podcast hosted by Shannon Sharpe, the rapper, 54, claimed that his ex abandoned him and their son Joey, now 33, after their son was diagnosed with Down syndrome at birth.
—Emma Aerin Becker, People.com, 17 Oct. 2024
Fat Joe revealed that his ex-significant other abandoned their son with Down syndrome.
—Marc Griffin, VIBE.com, 17 Oct. 2024
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Word History
Etymology
J. L. H. Down †1896 English physician
First Known Use
1961, in the meaning defined above
Dictionary Entries Near Down syndrome
Cite this Entry
“Down syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Down%20syndrome. Accessed 22 Nov. 2024.
Kids Definition
Down syndrome
nounˈdau̇n-
variants
or Down's syndrome
ˈdau̇n(z)-
: a genetic condition characterized especially by developmental delays, by distinctive physical traits (as short stature and upward slanting eyes), and by the presence of three chromosomes numbered 21 in human beings
Etymology
named for J.L.H. Down, 1828–1896, English doctor
Medical Definition
Down syndrome
noun
variants
or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, relatively small head, upward slanting eyes usually with epicanthal folds, flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21
called also Down, Down's, trisomy 21
More from Merriam-Webster on Down syndrome
Britannica.com: Encyclopedia article about Down syndrome
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