creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

People who are pregnant or breastfeeding should not take creatine. —Lauren O'Connor, Ms, Rdn, Health, 8 Apr. 2025

HCAs form when amino acids, sugars, and creatine (found in muscle) react with the high heat. —Roxana Ehsani, Verywell Health, 21 Mar. 2025

New research suggests overuse of products like whey powder or creatine may be affecting young people’s mental health as well as their their physical health. —Katie Camero, NBC News, 21 Feb. 2025

The researchers hope their study prompts consumers to question the claimed benefits of creatine supplements. —New Atlas, 20 Mar. 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine