cortisol

noun

cor·​ti·​sol ˈkȯr-tə-ˌsȯl How to pronounce cortisol (audio)
-ˌzȯl,
-ˌsōl,
-ˌzōl
: a glucocorticoid C21H30O5 produced by the adrenal cortex upon stimulation by ACTH that mediates various metabolic processes (such as gluconeogenesis), has anti-inflammatory and immunosuppressive properties, and whose levels in the blood may become elevated in response to physical or psychological stress

called also hydrocortisone

Examples of cortisol in a Sentence

Recent Examples on the Web
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The chic, award-winning, mold-inhibiting, purse-friendly and dermatologist recommended unit also comes with a space for an aromatherapy stone and essential oils to keep your cortisol levels low while micromanaging troublesome coworkers. Tanya Akim, Forbes, 21 Mar. 2025 However, if your body is under chronic stress, your cortisol levels will remain high for long periods, which disrupts the body’s ability to cope with and manage stress. Carrie Madormo, Rn, Mph, Verywell Health, 18 Mar. 2025 As back as 2006, a study published in the journal Physiology and Behavior identified a reduction in salivary cortisol levels among dogs who regularly engaged in human contact sessions. Jack Beresford, Newsweek, 11 Mar. 2025 Decreasing cortisol levels can calm your nervous system and potentially improve sleep.7 Magnesium also affects how well your body produces melatonin. Kirstyn Hill, Pharmd, Mph, Health, 10 Mar. 2025 See All Example Sentences for cortisol

Word History

Etymology

cortisone + -ol entry 1

First Known Use

1951, in the meaning defined above

Time Traveler
The first known use of cortisol was in 1951

Browse Nearby Words

Cite this Entry

“Cortisol.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cortisol. Accessed 26 Mar. 2025.

Medical Definition

cortisol

noun
: a glucocorticoid C21H30O5 produced by the adrenal cortex upon stimulation by ACTH that mediates various metabolic processes (as gluconeogenesis), has anti-inflammatory and immunosuppressive properties, and whose levels in the blood may become elevated in response to physical or psychological stress

called also hydrocortisone

More from Merriam-Webster on cortisol

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