complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

1

a

: complexity, intricacy

especially : a situation or a detail of character complicating the main thread of a plot

b

: a making difficult, involved, or intricate

c

: a complex or intricate feature or element

d

: a difficult factor or issue often appearing unexpectedly and changing existing plans, methods, or attitudes

2

: a secondary disease or condition developing in the course of a primary disease or condition

Synonyms

• complexity
• complicacy
• convolution
• difficulty
• intricacy

Examples of complication in a Sentence

The negotiations stalled when complications arose.

Pneumonia is a common complication of AIDS.

She experienced complications during her pregnancy.

The patient died of complications from surgery.

Recent Examples on the Web

This only adds to the complications for millennials and Gen Z, Bob Driscoll Senior Vice President and Director of Residential Lending at Rockland Trust, said. —Dan Perry, Newsweek, 28 Feb. 2025

There’s no specific treatment for measles, so doctors generally try to alleviate symptoms, prevent complications and keep patients comfortable. —Laura Ungar, Chicago Tribune, 27 Feb. 2025

During and after treatment, your healthcare team will monitor you closely for potential complications and related conditions, such as:18 Endometrial cancer: People who receive the drug Nolvadex (tamoxifen) for breast cancer have a higher rate of developing endometrial cancer. —Carrie Madormo, Rn, Health, 27 Feb. 2025

Three doctors who research or treat liver disease said that complications, such as infections or blood clots, are somewhat expected after a transplant, but patient outcomes are generally positive. —Aria Bendix, NBC News, 27 Feb. 2025

Word History

Etymology

Middle English complicacioun, borrowed from Late Latin complicātiōn-, complicātiō "folding together, conglomeration," from Latin complicāre "to fold together, fold up" + -tiōn-, -tiō, suffix of verbal action — more at complicate entry 2

First Known Use

15th century, in the meaning defined at sense 1a

Rhymes for complication

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

1

a

: an act or instance of complicating something

b

: a situation or detail of character that complicates a plot

c

: a complex feature or element

d

: something that makes a situation more complicated or difficult

we were unable to agree when complications arose

2

: a disease or bodily condition existing at the same time as and affecting the course or severity of another disease or condition

Medical Definition

complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

: a secondary disease or condition that develops in the course of a primary disease or condition and arises either as a result of it or from independent causes