channelopathy

noun

chan·​ne·​lop·​a·​thy ˌcha-nə-ˈlä-pə-thē 

plural channelopathies

: any of various disorders (such as epilepsy, migraine, cystic fibrosis, heart arrhythmia, and myotonia) caused by the malfunction of an ion channel

Word History

First Known Use

1993, in the meaning defined above

Medical Definition

channelopathy

noun

chan·​ne·​lop·​a·​thy ˌcha-nə-ˈlä-pə-thē 

plural channelopathies

: any of various disorders (such as epilepsy, migraine, cystic fibrosis, heart arrhythmia, and myotonia) caused by the malfunction of an ion channel

Long QT syndrome is a primary cardiac channelopathy with 6 identified chromosomal loci and 5 cardiac ion channel genes implicated.

—Michael J. Ackerman, The Journal of the American Medical Association