ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

ˈser-

plural ceramides

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids

The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.

—L. Stivitz

Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.

—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web

Key ingredients: Hyaluronic acid, ceramides, vitamin C | Size: 1 oz. —Brigitt Earley, Glamour, 27 Feb. 2025

The lightweight formula contains Japanese peony extract, niacinamide, ceramides, hyaluronic acid, vitamin C and peptides. —Celia Shatzman, Forbes, 26 Feb. 2025

Along with its moisturizing powerhouse combination of hyaluronic acid and ceramides, this body wash is enriched with antioxidants like vitamin A, vitamin B3 (niacinamide), vitamin C (known for its skin-brightening and antioxidant properties), and vitamin E (a free radical-fighting antioxidant). —Lauren Dana Ellman, Allure, 15 Feb. 2025

With hyaluronic acid, ceramides, and SPF 30, rest assured this drugstore classic will keep skin in tip-top shape. —Deanna Pai, Vogue, 14 Feb. 2025

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Rhymes for ceramide

• actinide
• aldehyde
• alkoxide
• alongside
• amplified
• arsenide
• beautified
• biocide
• butoxide
• calcified
• certified
• citywide

Medical Definition

ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue