bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

introduce into the economic bloodstream a large amount of money

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

There are three types of plague: bubonic plague, which is associated with enlarged lymph nodes called buboes; septicemic plague, which occurs when the bacteria enter the bloodstream; and pneumonic plague, which is when the infection enters the lungs. —Mary Kekatos, ABC News, 26 Aug. 2025

As a downstream effect, pain-soothing hormones are released into the bloodstream. —Lilian Raji, Forbes.com, 26 Aug. 2025

Heating hair products breaks down silicone compounds like D5 into ultrafine particles smaller than 100 nm in size – perfect for reaching the deepest parts of the lungs and even entering the bloodstream. —New Atlas, 23 Aug. 2025

The more sugar or carbohydrates a food contains, the higher the levels of glucose that make it into the bloodstream. —Angelica Bottaro, Verywell Health, 12 Aug. 2025

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system