baloxavir marboxil

noun

ba·​lox·​a·​vir mar·​box·​il bə-ˈläk-sə-ˌvir-mär-ˈbäk-səl 

variants or baloxavir

: an antiviral drug C₂₇H₂₃F₂N₃O₇S that is taken orally in the treatment of influenza A and B

Note: Baloxavir marboxil is a prodrug that undergoes metabolic conversion in the body to an acid which inhibits the action of an endonuclease necessary for viral replication.

In 2018, another inhibitor of the viral RNA polymerase, baloxavir marboxil, was approved in Japan and the United States for treatment of influenza A and B virus infections.

—P. Vasiliy Mishin

Examples of baloxavir marboxil in a Sentence

Recent Examples on the Web

Existing antiviral medications like oseltamivir (Tamiflu) and baloxavir marboxil may have limited effectiveness against H5N1 due to mutations. —Bruce Y. Lee, Forbes, 2 Dec. 2024

Laboratory testing suggests that other antiviral treatments – including a newer antiviral called baloxavir marboxil, or Xofluza – are still effective against the dual mutants, according to the CDC. —Deidre McPhillips, CNN, 14 June 2024

Word History

First Known Use

2018, in the meaning defined above