an·ti·de·pres·sant
ˌan-tē-di-ˈpre-sᵊnt 
ˌan-ˌtī-
ˌan-ˌtī-
: used or tending to relieve or prevent depression
antidepressant drugs
: an antidepressant drug see ssri, tricyclic antidepressant
Examples of antidepressant in a Sentence
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Emily Orofino, Vogue, 24 Jan. 2025
Summary Lexapro is an antidepressant medication in the SSRI class that is also taken to treat anxiety.
—Megan Nunn, Verywell Health, 12 Feb. 2025
Renée Onque, CNBC, 1 Apr. 2025
Key Takeaways Coffee can interfere with how your body absorbs or reacts to many common medications, including antidepressants, anticoagulants, and thyroid drugs.
—Sohaib Imtiaz, Verywell Health, 31 Mar. 2025
See All Example Sentences for antidepressant
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Adjective
The ayurvedic adaptogen is supported by three others, including shatavari—an herb proven to have antidepressant activity.
—Emily Orofino, Vogue, 24 Jan. 2025
Summary Lexapro is an antidepressant medication in the SSRI class that is also taken to treat anxiety.
—Megan Nunn, Verywell Health, 12 Feb. 2025
Noun
Additional medications that can cause drowsiness are antidepressants, antihistamines, allergy medications and more, according to Harvard Health Publishing.
—Renée Onque, CNBC, 1 Apr. 2025
Key Takeaways Coffee can interfere with how your body absorbs or reacts to many common medications, including antidepressants, anticoagulants, and thyroid drugs.
—Sohaib Imtiaz, Verywell Health, 31 Mar. 2025
See All Example Sentences for antidepressant
Cite this Entry
“Antidepressant.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antidepressant. Accessed 9 Apr. 2025.
Copy CitationMedical Definition
antidepressant
1 of 2 adjective
an·ti·de·pres·sant
ˌant-i-di-ˈpres-ᵊnt, ˌan-ˌtī-
variants
also antidepressive
: used or tending to relieve or prevent psychological depression : relating to, being, or utilizing an antidepressant
an antidepressant drug
antidepressant treatment
antidepressant
2 of 2 noun
variants
also antidepressive
: a drug used to treat psychological depression : an antidepressant drug
The dual-action antidepressant venlafaxine appears to demonstrate superior efficacy and higher rates of remission in severe depression as compared with either SSRIs such as fluoxetine or tricyclic antidepressants.—John Mann, The New England Journal of Medicine
John Mann, The New England Journal of Medicinecalled also energizer, psychic energizer, psychostimulant
see tricyclic antidepressantLove words? Need even more definitions?
Merriam-Webster unabridged
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