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Unbalanced hormones and overproduction of androgens like testosterone can contribute to acne.—Mary Choy, Verywell Health, 6 Mar. 2025 For example, some researchers theorize that a poor diet may cause bacteria to leak out of your gut, circulate throughout your body, and activate your immune system, thereby causing a spike in insulin, which could cause the ovaries to release androgens.—Julia Ries, Outside Online, 27 Feb. 2025 Spironolactone works by blocking aldosterone and decreasing androgen hormone production (testosterone) in the skin.9
There are two forms of spironolactone used for acne: oral (taken by mouth) and topical (applied to the skin).—Mary Choy, Verywell Health, 6 Mar. 2025 Stress produces more androgens, which are linked with the production of more sebum.—Anna Giorgi, Verywell Health, 27 Feb. 2025 See All Example Sentences for androgen
Note:
The term was apparently introduced in a short article "The Nomenclature of 'Male Hormones'" by the American Medical Society's Council on Pharmacy and Chemistry, published in the Journal of the American Medical Society, vol. 107, no. 3 (July 18, 1936), p. 212.
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