allostatic load

noun

: the cumulative adverse effect on the body when allostasis occurs too frequently (as when the body is subjected to repeated stressors) or is inadequate

Over weeks, months, or years, exposure to increased secretion of stress hormones can result in allostatic load and its pathophysiologic consequences.

—Bruce S. McEwen, New England Journal of Medicine, 15 Jan. 1998

Word History

First Known Use

1996, in the meaning defined above

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