acetaminophen

noun

acet·​amin·​o·​phen ə-ˌsē-tə-ˈmi-nə-fən How to pronounce acetaminophen (audio)
ˌa-sə-tə-
: a crystalline compound C8H9NO2 that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine to relieve pain and fever

Examples of acetaminophen in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Fevers can be treated with ibuprofen and acetaminophen, thank goodness; for everything else, good luck. Kathryn Schulz, New Yorker, 29 Mar. 2025 Many Back Pain Therapies Were Identified as Ineffective Three therapies were specifically identified as being ineffective for acute low back pain: exercise, steroid injections, and acetaminophen (Tylenol). Tom Gavin, EverydayHealth.com, 20 Mar. 2025 In the meantime, symptoms can be treated with over-the-counter drugs such as cough suppressants, nasal sprays and pain medicines like as ibuprofen and acetaminophen. Daryl Austin, USA TODAY, 12 Mar. 2025 Over-the-counter medications: Pain relievers like Tylenol (acetaminophen) and Advil (ibuprofen) can reduce mild to moderate muscle pain. Lindsay Curtis, Health, 24 Dec. 2024 See All Example Sentences for acetaminophen

Word History

Etymology

acet(yl) + amino + phen(ol)

Note: Shortened from N-acetyl-p-aminophenol. Acetaminophen was introduced as a generic name roughly coincident with the introduction of the trademark preparation Tylenol, which was first marketed as "Children's Tylenol Elixir" in 1955 by McNeil Laboratories. Synthesis of the substance, as acetylamidophenol, was first reported in Berichte der Deutschen Chemischen Gesellschaft, 11. Jahrgang (Jan.-Juni, 1878), p. 232-33 (H. N. Morse, "Ueber eine neue Darstellungsmethode der Acetylamidophenole"). Its antipyretic properties were recognized by the German physician Josef von Mering in the 1893 article "Beiträge zur Kenntniss der Antipyretica" (Therapeutische Monatshefte, 7, pp. 577-87)—he also refers to it as acetylamidophenol.

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of acetaminophen was in 1958

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Cite this Entry

“Acetaminophen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/acetaminophen. Accessed 9 Apr. 2025.

Kids Definition

acetaminophen

noun
acet·​amin·​o·​phen ə-ˌsēt-ə-ˈmin-ə-fən How to pronounce acetaminophen (audio)
: a crystalline compound used in medicine to relieve pain and fever

Medical Definition

acetaminophen

noun
acet·​amin·​o·​phen ə-ˌsēt-ə-ˈmin-ə-fən How to pronounce acetaminophen (audio) ˌas-ət- How to pronounce acetaminophen (audio)
: a crystalline compound C8H9NO2 that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine instead of aspirin to relieve pain and fever

called also paracetamol

see liquiprin, panadol, tylenol

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