Examples of SERM in a Sentence
Recent Examples on the Web
Ben Anderson: Well, tamoxifen comes from this group called Selective Estrogen Receptor Modulator, SERM.
—
Katie Hafner, Scientific American, 31 Oct. 2024
Examples are automatically compiled from online sources to
show current usage.
Read More
Opinions expressed in the examples do not represent those of Merriam-Webster or its editors.
Send us feedback.
Katie Hafner, Scientific American, 31 Oct. 2024
Dictionary Entries Near SERM
Cite this Entry
“SERM.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/SERM. Accessed 22 Dec. 2024.
Copy CitationMedical Definition
SERM
noun
: selective estrogen receptor modulator
Dramatic research findings have recently focused new attention on so-called designer estrogens, the medicines known more technically as selective estrogen receptor modulators (SERMs). These agents behave like estrogen in some tissues but block its action in others.—V. Craig Jordan, Scientific American
V. Craig Jordan, Scientific AmericanThe structural features of each SERM differ so that unique ligand-induced conformational changes take place in the ER [estrogen receptor], which are thought to be the likely basis for tissue-selective pharmacology. For example, raloxifene operates as an estrogen agonist in bone but as an antagonist in the breast and uterus.—Gideon A. Rodan et al., Science
Gideon A. Rodan et al., ScienceLove words? Need even more definitions?
Merriam-Webster unabridged
Share