polymerase chain reaction

noun

: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
abbreviation PCR

Examples of polymerase chain reaction in a Sentence

Recent Examples on the Web In the United Kingdom, the percentage of polymerase chain reaction tests that came back positive for SARS-CoV-2 peaked on 14 July at a level last seen in October 2023. Byjon Cohen, science.org, 21 Aug. 2024 The positivity rate for BayCare patients jumped from 2% early last month to roughly 13% as of Monday, according to results from polymerase chain reaction, or PCR, tests. Sam Ogozalek, Orlando Sentinel, 28 June 2024 The viral fragments were detected using quantitative polymerase chain reaction testing, which is known for its exceptional sensitivity in detecting even trace amounts of viral genetic material. Todd Cornish, The Conversation, 25 Apr. 2024 It should be noted that the polymerase chain reaction (PCR) test that was used can detect both live viruses and fragments of dead ones, and cannot differentiate between the two. Helen Branswell, STAT, 21 May 2024 See all Example Sentences for polymerase chain reaction 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'polymerase chain reaction.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1985, in the meaning defined above

Time Traveler
The first known use of polymerase chain reaction was in 1985

Dictionary Entries Near polymerase chain reaction

polymerase

polymerase chain reaction

polymeria

Cite this Entry

“Polymerase chain reaction.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polymerase%20chain%20reaction. Accessed 30 Sep. 2024.

Medical Definition

polymerase chain reaction

noun
: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, binding a primer to each single strand at the end of the given DNA segment where synthesis will start, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
abbreviation PCR

More from Merriam-Webster on polymerase chain reaction

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!