: any of a breed of tall massive powerful smooth-coated dogs
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After an exhaustive effort to keep them alive, all four of the surviving pups have been adopted into new homes, the Northwest Florida Great Dane Rescue wrote March 12 on Facebook.—Simone Jasper, Miami Herald, 21 Mar. 2025 Naomi Watts is transcendent as an author saddled with the depressed Great Dane of her late mentor (Bill Murray).—Randy Myers, The Mercury News, 7 Mar. 2025 There's also their unexpected meet-cute, involving a runaway Great Dane set loose on the streets of D.C., inspired by an experience of a woman Holmes knew.—Carly Tagen-Dye, People.com, 25 Feb. 2025 Looking at a Great Dane next to a Chihuahua can be pretty comical.—Clare Mulroy, USA TODAY, 10 Oct. 2024 See All Example Sentences for Great Dane
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