1
as in tainting
to affect slightly with something morally bad or undesirable
poisoning the minds of impressionable children with ethnic hatred
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2
as in polluting
to make unfit for use by the addition of something harmful or undesirable
exhaust fumes poisoning the air
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3
as in degrading
to lower in character, dignity, or quality
this party partisanship poisons the national debate we should be having about this urgent problem
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4
as in turning
to cause to have often negative opinions formed without sufficient knowledge
malicious rumors had poisoned many church members against the new pastor
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Merriam-Webster unabridged
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