1
as in to cease
to bring (as an action or operation) to an immediate end
the auto company is downsizing and will be packing up operations at the local plant
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2
as in to abandon
to stop doing (something) permanently
after two years of college, he decided to pack in that academic stuff and join the army
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as in to exit
to leave a place often for another
with the dinner conversation becoming more and more desultory, the time had clearly come to pack off
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Merriam-Webster unabridged
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