titration

noun

ti·​tra·​tion tī-ˈtrā-shən 

: a method or process of determining the concentration of a dissolved substance in terms of the smallest amount of reagent of known concentration required to bring about a given effect in reaction with a known volume of the test solution

Examples of titration in a Sentence

Recent Examples on the Web

What Hemings secured for herself through Jefferson, with an unknowable titration of guile and disgust and affection, Luce secures similarly through Mike. —Jesse Green, New York Times, 17 Apr. 2024

She’s mastered the precise titration between aspirational and relatable. —Véronique Hyland, ELLE, 30 Aug. 2023

The titration method is often employed by users to find their optimal dosage gradually. —Amber Smith, Discover Magazine, 24 July 2023

Dose titration was important. —Chris Fleming, SPIN, 4 Apr. 2023

Hi-Po Emulsi-D3TM is a concentrated, highly bioavailable liquid vitamin D supplement providing a variety of dosage and titration options. —Amber Smith, Discover Magazine, 15 Dec. 2022

So determining doses based on kilograms alone isn’t even a reliable metric for titration. —Benjamin Adams, Forbes, 5 July 2022

The medication also requires titration over a few weeks to months for optimal adherence. —Arielle Mitropoulos, ABC News, 4 June 2021

While doctors consider a patient’s weight in some cases, weight is generally subsumed into larger considerations of therapeutic index and titration when determining the right dose for a patient. —Richard Klasco, New York Times, 8 June 2018

Word History

First Known Use

circa 1859, in the meaning defined above

Kids Definition

titration

noun

ti·​tra·​tion tī-ˈtrā-shən 

: the process of finding out the strength of a liquid mixture (as of an acid in water) by dripping another mixture (as of a base) of known strength into a known amount of the first mixture with usually another substance that will change color and measuring the amount of the second mixture required to make the first mixture change color

Medical Definition

titration

noun

ti·​tra·​tion tī-ˈtrā-shən 

: a method or the process of determining the concentration of a dissolved substance in terms of the smallest amount of a reagent of known concentration required to bring about a given effect in reaction with a known volume of the test solution

especially : the analytical process of successively adding from a burette measured amounts of a reagent to a known volume of a sample in solution or a known weight of a sample until a desired end point (as a color change) is reached