leukotriene

noun

leu·​ko·​tri·​ene ˌlü-kō-ˈtrī-ˌēn How to pronounce leukotriene (audio)
: any of a group of eicosanoids that participate in allergic responses (such as bronchial constriction)

Examples of leukotriene in a Sentence

Recent Examples on the Web Leukotriene Inhibitors Medications like montelukast can help manage respiratory symptoms by blocking leukotrienes, which are involved in inflammatory responses. Sarah Jividen, Verywell Health, 11 July 2024 Other medications include what are known as leukotriene modifiers, which block the action of inflammatory chemicals the immune system produces in the presence of allergens. Jeffrey Kluger, TIME, 25 June 2024 People with asthma may require higher doses of inhaled corticosteroids or the addition of other medicines, such as leukotriene inhibitors. Ray Hainer, Health, 3 May 2024 These medications block leukotrienes—chemicals your body produces when it’s exposed to allergens—from binding to your cells. Joanna Thompson, Scientific American, 19 Jan. 2024 What leukotriene modifiers such as Singulair are not supposed to do is cross the blood-brain barrier. Joanna Thompson, Scientific American, 19 Jan. 2024 Other protiens found in their saliva, such as tryptase and leukotrienes, can directly cause itchiness. Emily Shiffer, Health, 7 Mar. 2023 The risk was lower in people who took a drug that blocked leukotrienes. Stacey Burling, Philly.com, 8 June 2018 The Temple researchers tried the drug because of their previous work on leukotrienes, inflammatory molecules that don’t work properly in Alzheimer’s disease or frontotemporal dementia. Stacey Burling, Philly.com, 8 June 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'leukotriene.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1979, in the meaning defined above

Time Traveler
The first known use of leukotriene was in 1979

Dictionary Entries Near leukotriene

Cite this Entry

“Leukotriene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leukotriene. Accessed 5 Nov. 2024.

Medical Definition

leukotriene

noun
leu·​ko·​tri·​ene ˌlü-kə-ˈtrī-ˌēn How to pronounce leukotriene (audio)
: any of a group of eicosanoids that are generated in basophils, mast cells, macrophages, and human lung tissue by lipoxygenase-catalyzed oxygenation especially of arachidonic acid and that participate in allergic responses (as bronchoconstriction in asthma) see slow-reacting substance of anaphylaxis

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