fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Inside the backpack, the agency said, were eight bundles of fentanyl. Teri Figueroa, San Diego Union-Tribune, 24 Feb. 2025 Nearly 1,000 pounds of fentanyl – the drug that has become the center point of the substance abuse issue in the U.S. in recent years – was seized along the southwestern border in January 2025. Liam Hibbert | The Center Square Contributor, Washington Examiner - Political News and Conservative Analysis About Congress, the President, and the Federal Government, 23 Feb. 2025 Talis Noel, 48, allegedly had about 2 ounces of fentanyl, with smaller amounts of cocaine, and methamphetamine. Bay City News Service, The Mercury News, 22 Feb. 2025 Subsequent research showed that the increase in overdoses was likely due to the introduction of fentanyl, not Measure 110. Alex Fitzpatrick, Axios, 20 Feb. 2025 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

Browse Nearby Words

Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 10 Mar. 2025.

Medical Definition

fentanyl

noun
fen·​ta·​nyl ˈfent-ᵊn-ˌil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

More from Merriam-Webster on fentanyl

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!