: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
An airborne alien virus, designed to rewrite DNA, had been released over New York City in 1946 and spread globally, infecting tens of thousands worldwide. Jennifer Ouellette, WIRED, 25 Jan. 2025 The resilience Lucy Jones talks about and eloquently writes about — the DNA of community — was on display Jan. 8 at the Pasadena Convention Center, where evacuees summoned the strength to deal with loss and uncertainty while service organizations stepped up and volunteers pitched in. Steve Lopez, Los Angeles Times, 24 Jan. 2025 Prime editing offers more accurate and flexible DNA modifications compared to traditional CRISPR-Cas9 systems, allowing for insertions, deletions, and base substitutions without inducing double-strand breaks. William A. Haseltine, Forbes, 24 Jan. 2025 In the lab, researchers can extract, splice and analyze genomic sequences from blood, saliva, tissues, DNA and other biospecimens that are collected from South Florida, Africa, South America, Asia and other parts of the world. Michelle Marchante, Miami Herald, 24 Jan. 2025 See all Example Sentences for DNA 

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Dictionary Entries Near DNA

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 28 Jan. 2025.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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