ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

ˈser-

plural ceramides

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids

The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.

—L. Stivitz

Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.

—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web

Key ingredients: ceramide, hyaluronic acid | Fragrance-free: yes Frequently Asked Questions What is the best facial cleanser for mature skin? —Christa Joanna Lee, Allure, 23 Jan. 2025

Key Ingredients: Peptide complex, apple fruit extract, shea butter, ceramides How to Apply: Starting with clean skin on the neck and chest, gently massage the product upward from the chest toward the jawline. —Kiana Murden, Vogue, 20 Jan. 2025

Look for ingredients like hyaluronic acid, glycerin, and ceramides. —Amanda Svachula, Health, 13 Jan. 2025

Ingredients like growth factors, vitamin C and ceramides, combined with treatments like Intense Pulsed Light (IPL) or Sculptra, can address common concerns while supporting your skin’s natural regeneration. —Eva Crouse, Flow Space, 6 Jan. 2025

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Medical Definition

ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue